Abstract: Based on the HFR method for bound states and Distorted –Wave method for continuous states, photoionization cross sections that describe level to level transitions of He-like Rb and He –like Nb ions have been calculated. In the calculation, configuration interactions between bound states have been considered. The included configurations of the process are 1s nl 1s e l± 1(1 n 6, 0 n-1), and the energy range of free electron is 0 ~10 times the ionization energy. The computational error and the data accuracy are discussed. Also the results that have been summed over final states are provided.