Abstract: Pyrotechnic explosion pumping method is one of the solutions to make miniature and portable laser. A chemical reagent used to pump Nd glass laser was prepared. The main ingredients of the reagent were metal powders and alkali metals’ oxysalts. The experimental apparatus of pyrotechnically pumped Nd glass laser was designed. The laser consisted of a f8 mm×100 mm Nd glass rod tightly encircled with pump sources by the side. The resonator contained a high reflection plane mirror and a concave mirror of 98% reflectivity. Output experiment used two reagents A and B with different near-infrared radiation intensity, reagent A output 29 mJ laser beam with wavelength 1 053 nm, and B didn’t output laser. Pumping radiation intensity thresholds of the two pump sources were computed. Reagent A gives