Abstract: Self-organized nanostructures were observed on the surface of ZnSe crystal after irradiation by a focused beam of a femtosecond Ti: sapphire laser with a repetition rate of 250 kHz. For a linearly polarized femtosecond laser, a periodic nanograting structure on the ablation crater surface was promoted. The period of these self-organization structures is about 160 nm. The grating orientation can be adjusted by changing the laser polarization direction. A long range Bragg-like grating formed by moving the sample at the speed of 10 μm/s in the horizontal plane. For a circularly polarized laser beam, uniform spherical nanoparticles formed.