Abstract: A new method for ICF fuel content measuring based on laser Raman scattering is presented, which can directly and non-destructively analyzes deuterium gas content in shells. Since the incident and scattered lights would traverse through the shell wall, therefore the material performance of the shell will greatly affect the measured results. Thus corresponding experiments have been done using a confocal laser Raman microscope, and the factors that will influence the results, such as shells florescence, laser wavelength and power, grating resolution,and system confocal performance, have been investigated, which proves the feasibility of the method.