Abstract: The multi-non-uniform grid model of parabolic equation method is presented to solve the radio wave propagation problems with multiple sources in three-dimensional space. Multiple simulation spaces are constructed with different non-uniform grid for each source in corresponding coordinate system. In addition, a parallel technique is employed into multi-non-uniform grid model for the parallel computing of multiple sources problems in three-dimensional space. The radio wave propagation problem with four sources is simulated. The results show that the electromagnetic distribution characteristics of multi-source can be accurately solved via this multi-non-uniform grid model, and in this case, the parallel technique makes the calculation speed of parabolic equation 2.41 times faster, which greatly improves the solution efficiency of 3D multi-source problems.