Abstract: In this paper, in the case of considering the mutual inductance, the linear, L and U1 connecting structures of the pulse forming network are simulated by PSpice software. At the same time, a three-dimensional model of five different connecting structures of pulse forming network are established and simulated with the transient field-circuit synchronous collaborative simulation methodology. Then, the experiments of the PFNs with the five different connecting structures are carried out. The experimental results reveal that the rise time of PFNs with five different connecting structures is about 45 ns, the pulse half-high widths of the PFNs with U1-type, U2-type and U3-type structures are 166 ns, 158 ns and 154 ns, respectively. And the flat-tops of the output waveform are more fluctuant. Finally, the simulation results obtained by the circuit and transient field-circuit synchronous collaborative simulation methods and the experimental results are analyzed and compared. The results show that the working process and output waveform of the pulse forming network are well simulated with the transient field-circuit synchronous collaborative simulation methodology, and the matching load and the switch inductance in the experiment are bigger than that in the simulation, and it is of great significance that the U-type structure of PFN is conducive to the compact structure and miniaturization of the pulsed power source system in engineering applications.