Abstract: The optimization of the core periodical physical flux map test could be done using the SOPHORA on-line core monitoring system developed by China General Nuclear Power Group. This system can perform the calculation of 3D online monitoring, core operation analysis in depth, core subsequent state simulation and prediction, the core operation strategy generation and optimization, and so on. Combining on-line theoretical calculation and instrument measurement, SOPHORA can get the best estimated measured power distribution. By coupling the self-reliant flux map processing code MAPLE and the physics experiment processing code HOLLY, one can analyse the feasibility of delay of RPN11 test interval. A single point ex-core calibration method has been developed in SOPHORA, which can reduce the frequency of carrying out RPN12 test. The results of sensitivity study of RPN11 and RPN12 test measurement process show that it is possible to extend the time interval of RPN11 test and to cancel some of the RPN12 test experiment.