Abstract: The power cord of much electronic equipment is twisted-wire pair. Being a special structure, to calculate its load response by radiation is very cumbersome. In many cases, one of the twisted-wire pair is connected with ground, and the height from the ground to twisted-wire pair is more than the spacing between twisted-wire pair. For this model, based on the Taylor model, this paper proposed a simplified model which was calculated the load response of twisted-wire pair by radiation. The twisted-wire pair model was simplified as a single-wire model, its electric current was doubled. By solving the BLT equation, the load response of twisted-wire pair was calculated. The model was proved by comparing with the CST simulation results.