Feasibility analysis for radionuclide therapy dose measurement based on Cerenkov radiation

Ai Yao; Shu Diyun; Gong Chunhui; Geng Changran; Zhang Xudong; Tang Xiaobin

doi:10.11884/HPLPB201729.170236

Volume 29 Issue 12

Feb. 2018

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Article Navigation > High Power Laser and Particle Beams > 2017 > 29(12): 126011

Liu Jiao, Yan Liping, Li Bin, et al. Artificial neural network modeling of component nonlinear behavior and application in conducted interference analysis[J]. High Power Laser and Particle Beams, 2015, 27: 103212. doi: 10.11884/HPLPB201527.103212

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Ai Yao, Shu Diyun, Gong Chunhui, et al. Feasibility analysis for radionuclide therapy dose measurement based on Cerenkov radiation[J]. High Power Laser and Particle Beams, 2017, 29: 126011. doi: 10.11884/HPLPB201729.170236

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Feasibility analysis for radionuclide therapy dose measurement based on Cerenkov radiation

doi: 10.11884/HPLPB201729.170236

1.
Department of Nuclear Science and Engineering,Nanjing University of Aeronautics and Astronautics,Nanjing 210016,China;
2.
Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions,Nanjing 210016,China

Received Date: 2017-06-21
Rev Recd Date: 2017-08-14
Publish Date: 2017-12-15

Abstract

Abstract

This paper aims to determine the relationship between the emission of Cerenkov photon number and radiation dose from internal radionuclide and proposes, a potential dosimetry based on Cerenkov radiation for radionuclide therapy. Water and thyroid phantoms were used to simulate the distribution of Cerenkov photon number and dose deposition produced by radionuclide 131I through Geant4 toolkit, and the relationship between Cerenkov photon number and dose deposition was quantitatively analyzed. The calculation results show that the Cerenkov photon number and dose deposition have the same distribution trend in water phantom, and this relative distribution relationship also exists in thyroid phantom. Moreover, the Cerenkov photon number exhibits a specific quantitative relation to dose deposition.
- Cerenkov radiation,
- internal dose,
- radionuclide,
- radionuclide therapy,
- Monte Carlo method

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