Detection of spike protein of SARS-CoV-2 by surface enhanced Raman spectroscopy

Huang Jinglin; Zhou Minjie; Le Wei; Chen Guo; Ni Shuang; Niu Gao; Li Zeyu; Zhao Zongqing; He Zhibing; Li Bo; Zhao Songnan; Zhang Baohan; Du Kai

doi:10.11884/HPLPB202032.200145

Volume 32 Issue 6

May 2020

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Huang Jinglin, Zhou Minjie, Le Wei, et al. Detection of spike protein of SARS-CoV-2 by surface enhanced Raman spectroscopy[J]. High Power Laser and Particle Beams, 2020, 32: 069001. doi: 10.11884/HPLPB202032.200145

Citation:

Huang Jinglin, Zhou Minjie, Le Wei, et al. Detection of spike protein of SARS-CoV-2 by surface enhanced Raman spectroscopy[J]. High Power Laser and Particle Beams, 2020, 32: 069001. doi: 10.11884/HPLPB202032.200145

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Detection of spike protein of SARS-CoV-2 by surface enhanced Raman spectroscopy

doi: 10.11884/HPLPB202032.200145

Research Center of Laser Fusion, CAEP, P. O. Box 919-988, Mianyang 621900, China

Received Date: 2020-05-20
Rev Recd Date: 2020-05-30
Publish Date: 2020-05-12

Abstract

Abstract

The development of rapid detection technique with high sensitivity and high veracity for SARS-CoV-2 is of great importance for the prevention and control of epidemic. In this work, the trace spike protein (S protein) of SARS-CoV-2 in human saliva was detected by surface enhanced Raman spectroscopy (SERS) technique. Significant differences can be found between the Raman spectra of the S protein stained saliva sample and the primitive saliva sample. These results will lay the foundation for the future rapid detection of SARS-CoV-2 by SERS technique.
- surface enhanced Raman spectroscopy,
- SARS-CoV-2,
- spike protein,
- rapid detection

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References(5)

References

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