Yan Congchong, Qiu Rui, Xie Wenzhang, et al. Nanodosimetry Monte Carlo simulation of DNA strand breaks by low-energy electron[J]. High Power Laser and Particle Beams, 2013, 25: 153-157. doi: 10.3788/HPLPB20132501.0153
Citation:
Yan Congchong, Qiu Rui, Xie Wenzhang, et al. Nanodosimetry Monte Carlo simulation of DNA strand breaks by low-energy electron[J]. High Power Laser and Particle Beams, 2013, 25: 153-157. doi: 10.3788/HPLPB20132501.0153
Yan Congchong, Qiu Rui, Xie Wenzhang, et al. Nanodosimetry Monte Carlo simulation of DNA strand breaks by low-energy electron[J]. High Power Laser and Particle Beams, 2013, 25: 153-157. doi: 10.3788/HPLPB20132501.0153
Citation:
Yan Congchong, Qiu Rui, Xie Wenzhang, et al. Nanodosimetry Monte Carlo simulation of DNA strand breaks by low-energy electron[J]. High Power Laser and Particle Beams, 2013, 25: 153-157. doi: 10.3788/HPLPB20132501.0153
Key Laboratory of High Energy Radiation Imaging Fundamental Science for National Defense,Key Laboratory of Particle and Radiation Imaging Tsinghua University,Ministry of Education,Department of Engineering Physics,Tsinghua University,Beijing 100084,China
In order to simulate the yields of low-energy electrons induced DNA strand breaks, according to D. Emfietzoglous dielectric response theory and Borns correction model, we calculated the inelastic reaction cross sections for low-energy electron transport in liquid water. The physic module on the basis of the Geant4-DNA was established, and also the pre-chemical, chemical, DNA damage analysis modules were established. The yields of DNA strand breaks caused by the different energy electrons uniformly irradiating DNA were simulated, and the simulation results are in good agreement with the published experimental data.
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