The monolayer water soluble thiol pretected cluster is doped in the agar-gelatin complex foam target materials. The TEM photographes indicate that, after doping, the density along axial direction of the complex foam is uniform and the microstructure of the complex foam is not affected evidently by Au MPC. When the density of the doped foam is as low as 5.8 mg/cm3 and the mass percent of the dopant is as high as 30%, Au MPC does not assemble or sedimentate in the agar-gelatin foam. The preparation procedure of Au MPC doped agar-gelatin complex foam is studied, and the doped foams with the density less than 10 mg/cm3, cell sizes less than 100 mm are prepared with water as the solvent.